Symptoms and conditions


The most frequent reasons for consultation on paediatric rheumatology are:

  • Inflammation and/or joint pain.
  • Limp.
  • Recurrent fever.
  • Muscular weakness.
  • Erythema nodosum and other inflammatory skin lesions.
  • Raynaud phenomenon.
  • Recurrent aphthous stomatitis.


  • Juvenile Idiopathic Arthritis (JIA).
  • Juvenile Dermatomyositis (JDM) and inflammatory myopathies in paediatrics.
  • Childhood-onset Systemic Lupus Erythematosus (cSLE). Neonatal lupus.
  • Paediatric antiphospholipid syndrome (pAPS).
  • Localized scleroderma in childhood (morphea).
  • Juvenile systemic sclerosis (JSSc).
  • Rare Juvenile Primary Systemic Vasculitis in children (Kawasaki disease, Henoch-Schönlein purpura, Polyarteritis nodosa, Antineutrophil cytoplasmic autoantibodies (ANCA)-associated vasculitis, Takayasu disease, Primary angiitis of the central nervous system).
  • Paediatric Sjögren syndrome.
  • Mixed connective tissue disease.
  • Arthritis associated with inflammatory bowel disease and other gastrointestinal diseases.
  • Rheumatic fever and post-streptococcal reactive arthritis.
  • Behçet disease.
  • Chronic non-bacterial osteomyelitis (CNO). Chronic recurrent multifocal osteomyelitis (CRMO).
  • Uveitis associated with rheumatic diseases.
  • Autoinflammatory diseases (PFAPA syndrome, Familial Mediterranean Fever (FMF), Mevalonate kinase deficiency (MKD) or Hyper IgD syndrome (HIDS), Cryopyrin associated periodic syndromes (CAPS), Blau’s disease, Deficiency of Adenosine Deaminase 2 (DADA2), recurrent fever with undefined genetic cause).