Symptoms and conditions

Symptoms

The most frequent reasons for consultation on paediatric rheumatology are:

• Inflammation and/or joint pain.
• Limp.
• Recurrent fever.
• Muscular weakness.
• Erythema nodosum and other inflammatory skin lesions.
• Raynaud phenomenon.
• Recurrent aphthous stomatitis.

Diseases

• Juvenile Idiopathic Arthritis (JIA).
• Juvenile Dermatomyositis (JDM) and inflammatory myopathies in paediatrics.
• Childhood-onset Systemic Lupus Erythematosus (cSLE). Neonatal lupus.
• Paediatric antiphospholipid syndrome (pAPS).
• Localized scleroderma in childhood (morphea).
• Juvenile systemic sclerosis (JSSc).
• Rare Juvenile Primary Systemic Vasculitis in children (Kawasaki disease, Henoch-Schönlein purpura, Polyarteritis nodosa, Antineutrophil cytoplasmic autoantibodies (ANCA)-associated vasculitis, Takayasu disease, Primary angiitis of the central nervous system).
• Paediatric Sjögren syndrome.
• Mixed connective tissue disease.
• Arthritis associated with inflammatory bowel disease and other gastrointestinal diseases.
• Rheumatic fever and post-streptococcal reactive arthritis.
• Behçet disease.
• Chronic non-bacterial osteomyelitis (CNO). Chronic recurrent multifocal osteomyelitis (CRMO).
• Uveitis associated with rheumatic diseases.
• Autoinflammatory diseases (PFAPA syndrome, Familial Mediterranean Fever (FMF), Mevalonate kinase deficiency (MKD) or Hyper IgD syndrome (HIDS), Cryopyrin associated periodic syndromes (CAPS), Blau’s disease, Deficiency of Adenosine Deaminase 2 (DADA2), recurrent fever with undefined genetic cause).